Manual Pinch Valve

The ARTeSYN® Pinch Valves (PVs) are designed for Single-Use flow control in Biopharmaceutical manufacturing. ARTeSYN Single-Use valves outperform other pinch valves because of easy maintenance, simple installation, compact and durable design, and 0 to 100% fluid control.

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PVs are non-product contact and meant for tube and hose sizes from ¼” to 1" ID. The Single-Use Pinch Valves (PVs) are matched to use on existing tubing to provide flow control and automation where it did not previously exist. These valves have a non-rotating hemispherical plunger design that allows for very fine fluid control. They are available with ON/OFF and modulating pneumatic actuation, as well as multiple brands of electronic feedback indicators. The ARTeSYN® Pinch Valves can be easily adapted for mounting to skids or fixtures and thanks to the ARTeSYN® design allow for rapid and easy tubing changes.


  • Virtually eliminates dead-leg
  • Precise flow control
  • Simplified construction
  • Small size
  • Progressive flow curve
  • Disposable liners - no cleaning necessary
  • Operator ease of use
  • Highest closure resistance & reliability
  • Consistent flow over pinching cycle
  • Minimized tubing wear
  • Easy verification of valve position for operators
  • Eliminate unnecessary junctions
  • Reduced validation effort
  • Reduce consumable complexity & cost
  • Reduced operator errors with automated fluid control

Upstream applications

Media and buffer preparation
Cell clarification/harvest

Downstream applications

Downstream Filtration
Downstream Chromatography
Downstream Finish Filling
Downstream Buffer Exchange
Downstream Virus Inactivation
Downstream Concentration
Downstream Fractionation
Downstream Transfer