The steam2® valve delivers an engineered design with minimized dead leg providing a solution for flexible and safe aseptic fluid transfer at industrial scale. Available with progressive manual actuation in a variety of stainless steel sanitary connection types, it allows for the reliable connection of two stainless steel flange ends.
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The single-use flow path made out of ARTeSIL® molded silicone has a seal-free actuation mechanism making it safe and reliable at point of use. The single-use tubing end is braided silicone available in 3/8 in., 1⁄2 in., 3⁄4 in., and 1 in. internal diameter.

With a range of sizes, the ARTeSYN® steam2® valves are suitable for use in liquid or gas transfer applications from upstream processing, downstream processing through to formulation and filling. The steam2® valves are suited to enable aseptic transfers of fluid from traditional to single use process wetted parts.


  • Safe, reliable and simplified processing
  • Simplified material validation
  • Eliminated cross contamination risk
  • Reduced down time
  • Unrestricted flow throughput
  • Simple reduced risk concept
  • Process flexibility
  • Increased sterility assurance
  • Facilitated sterilization validation
  • Closure resistance and reliability
  • Suits both pressurized and unpressurized applications

Upstream applications

Media and buffer preparation
Cell clarification/harvest

Downstream applications

Downstream Chromatography
Downstream Buffer Exchange
Downstream Virus Inactivation
Downstream Concentration
Downstream Fractionation
Downstream Transfer
Downstream Finish Filling